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pentobarbital will decrease the level or outcome of solifenacin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.pentobarbital will minimize the level or influence of irinotecan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.pentobarbital increases toxicity of buprenorphine, extensiv